I upgraded to one of Mission Workshop's waxed canvas Fitzroy bags a couple months back and I love it. It's waterproof like all their bags, but the canvas exterior gives it a more natural feel. There's a big laptop sleeve built in with a sheet of carbon fiber to add some protection. All their bags are wonderfully designed for bike commuting, although I could see myself using this one regardless. For travel, I've already used this bag a couple times for long weekend trips and found it spacious enough to avoid bringing another carry-on. The price tag is a bit high, but consider that these are U.S. made and guaranteed for life. Link