So generally if I want to brand a simple page I would use one @fontface for titles and then use this fontstack for body. With the web being responsive it is hard to design so specifically with type (as you get outliers and other annoyances as you scale the page), so I just try to get it looking the best I can possibly on the system I'm on and then see if the design looks look acceptable on other systems as well (generally they do).
So generally if I want to brand a simple page I would use one @fontface for titles and then use this fontstack for body. With the web being responsive it is hard to design so specifically with type (as you get outliers and other annoyances as you scale the page), so I just try to get it looking the best I can possibly on the system I'm on and then see if the design looks look acceptable on other systems as well (generally they do).